منابع مشابه
Type C viral antigens in man. I. Antigens related to endogenous primate virus in human tumors.
Partially purified extracts from 33 human tumors of several histologic types were used as competing antigens in a radioimmunoassay for the p30 protein of an endogenous primate type C virus (M7). Antigens immunologically related to the p30 protein of the M7 virus were detected in two tumors. Like viral p30 antigens previously identified in tissues of several other primates, the antigens found in...
متن کاملPrimate Tissues
A B S T R A C T The specific activity of the branchedchain a-keto acid (BCKA) dehydrogenases was measured in normal tissues of the rat, monkey, and man, and in cirrhotic human liver. In the rat, specific activity of the dehydrogenases in liver, kidney, and muscle averaged 33, 26, and 0.4 U/g wet tissue, respectively; proportion of the body's content of the enzyme located in these three organs w...
متن کاملSpecificity of in vitro binding of primate Type C viral RNA and the homologous viral p12 core protein.
The binding of type C viral p12 proteins to purified viral RNA has been examined in vitro with the use of a family of closely related infectious primate type C viruses--the woolly monkey (SSAV) and gibbon (GALV) group. This in vitro protein-RNA binding is type specific. The system should serve as a model for studies of the evolution of nucleic acid binding proteins.
متن کاملELISA for the detection of antigens cross-reacting with primate C-type viral proteins (p30,gp70) in human leukemic sera.
A number of methods have been applied in the past to the serologie identifieation and characterization of C-type viral proteins. The most specifie and most sensitive system used has been the competition radioimmunoassay (RIA). This assay detects group specific as well as interspecies activity of the major viral proteins (Parks and Scolnick 1972; Strand and August 1973). Disadvantages of this as...
متن کاملRadioimmunoassay of Mammalian Type C Viral Proteins
A radioimmunoassay specific for a murine leukemia virus structural protein, the gs antigen, detects an antigenic reactivity in normal murine cells in culture and natural tissues. The assay was shown to measure an antigen that is highly related to the virion protein as shown by absorption tests, immunoadsorbent chromatography, and by analysis of linearized dose-response curves. These findings co...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1974
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.71.9.3721